Postoperative acute kidney injury is a major concern after cardiac surgery and is associated with increased costs and length of stay.10
Haemodynamic instability during cardiac surgery is associated with AKI and other complications (myocardial injury, stroke) after surgery8, 11-17 negatively impacting patient and healthcare system outcomes.1
The reported prevalence of cardiac surgery-associated AKI is up to 40%.21,22
Nearly one out of every five cardiac surgery patients require readmission, with significant health and economic implications.7
1/10 cardiac surgery patients experience prolonged time in hospital due to organ dysfunction and/or multi-organ failure. Hemodynamic instability increases the cost of ICU treatment and overall hospital costs.5
What does the latest research tell us about the risks and impact of AKI and other complications after cardiac surgery?
Cardiac surgery is associated with an increased risk of AKI, stroke and mortality 22, 24, 8
22. Lau D, et al. J Thorac Cardiovasc Surg 2021;162:880-887.
24. Ngu JMC, et al. Anesthesiology 2020; 132:1447–57. 8. de la Hoz MA, et al. Anesthesiology 2022;136:927-939.
As haemodynamic instability increases the risk for AKI, end-organ injury and other complications, the Society for Enhanced Recovery After Cardiac Surgery (ERAS® Cardiac) now recommends goal-directed fluid therapy to avoid hypotension and low cardiac output .23
Would you like to enable your team to detect and mitigate haemodynamic instability, which is associated with an increased risk of AKI?
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Acumen Hypotension Prediction Index (HPI) software
Acumen HPI software is effective in detecting haemodynamic instability and substantially reducing the duration of intraoperative hypotension.
*Data on file, HCP survey/survey of cardiac surgeons.
Medical device for professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).
References
1. Silver SA, et al. Nephron. 2017;137(4):297301.
2. Hobson C, Ozrazgat-Baslanti T, Kuxhausen A, et al. Ann Surg. 2015;261(6):1207-1214.
3. Collister D, et al. Clin J Am Soc Nephrol. 2017;12(11): 1733-1743.
4. Alshaikh HN, et al. Ann Thorac Surg. 2018;105(2):469-475.
5. Tribuddharat S, et al. Medical Devices: Evidence and Research 2021;14: 201–209.
6. Crawford TC, et al. Ann Thorac Surg 2017;103: 32–40.
7. Iribarne A, et al. Ann Thorac Surg 2014; 98: 1274–1280.
8. de la Hoz MA, et al. Anesthesiology 2022;136: 927–939.
9. Khuri SF, et al. Ann Surg 2005; 242:326–343.
10. Ramos KA, et al. Braz J Cardiovasc Surg 2018;33:454-461.
11. Zarbock A & Engelman DT. J Thorac Cardiovasc Surg 2020;159: 1878-1879.
12. Maheshwari A, et al. Br J Anaesthesia 2017;119: 40–49.
13. Sun LY, et al. Anesthesiology 2018; 129:440-7.
14. Smeltz AM, et al. J Cardiothorac Vasc Anesth 2018;32: 1214-1224.
15. Liu YL, et al. Nephrol Dial Transplant 2009;24:504–511.
16. Molnar Z, et al. Br J Anaesth 2020;125: 419-423.
17. Vos JJ & Scheeren TW. Indian J Anaesth 2019;63:877-85.
18. Landais, et al. Anaesthesia Critical Care & Pain Medici. 2017;36(3): 151-155.
19. Sessler DI, Khanna AK. Intensive Care Med. 2018;44(6):811-822.
20. Smilowitz NR, et al. JAMA Cardiol. 2017;2(2):181-187.
21. Chew & Hwang. JCVA 2018.
22. Lau D et al. J Thorac Cardiovasc Surg. 2021;162(3): 880-887.
23. Brown JK et al. J Cardiothoracic & Vascular Anesthesia; 2023.
24. Ngu, Janet M C et al. Anesthesiology vol. 132,6 (2020): 1447-1457.
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