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Research has shown that neuronal ischemia is negatively associated with survival in ICU patients2 and prolonged cerebral desaturations are associated with:

• Post-op delirium3,4 and cognitive dysfunction5
• Extended time on mechanical ventilation1
• Extended ICU and hospital LOS1,6

Maintaining SctO2 values within target ranges helps to mitigate incidences of cerebral desaturation events.5,7

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1. Deschamps A, Hall R, Grocott H, et al. Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial. Anesthesiology. 2016; 124(4):826-836.
2. Sharshar T, Annane D, de la Grandmaison GL, et al. The neuropathology of septic shock. Brain Pathol. 2004;14(1):21-33.
3. Wood MD, Maslove D, Muscedere J, et al. Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study. J Crit Care. 2017;41:289-295.
4. Lee KF, Wood MD, Maslove DM, et al. Dysfunctional cerebral autoregulation is associated with delirium in critically ill adults. J Cereb Blood Flow Metab. 2019;39(12):2512-2520.
5. Tang L, Kazan R, Taddei R, et al. Reduced cerebral oxygen saturation during thoracic surgery predicts early postoperative cognitive dysfunction. British Journal of Anaesthesia. 2012;08(4):623-629.
6. Murphy GS, Szokol JW, Marymont JH, et al. Cerebral oxygen desaturation events assessed by near-infrared spectroscopy during shoulder arthroscopy in the beach chair and lateral decubitus positions. Anesth Analg. 2010; 111(2):496-505.
7. Fischer GW, Lin HM, Krol M, et al. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. J Thorac Cardiovasc Surg. 2011;141(3):815-821.